Nicotinamide
CAS No. 98-92-0
Molecular formula C6H6N2O
Nicotinamide, also known as niacinamide and nicotinic acid amide, is the amide of nicotinic acid (vitamin B3 / niacin). Nicotinamide is a water-soluble vitamin and is part of the vitamin B group.
Nicotinamide has been shown to improve the ability of the epidermis, the upper-most layer of the skin, to retain moisture.
The benefits to the skin after application of nicotinamide can be useful for patients with atopic dermatitis, who often experience dry, irritated skin when the disease flares, this could also become another promising treatment for aging skin which oftentimes becomes dry and flaky as we age.
Nicotinamide has also been shown to be an effective skin lightening agent, especially for skin conditions where hyperpigmention may occur on the face or other visible parts of the body.
Topical nicotinamide has also been shown to have anti-inflammatory properties, which makes it a potential treatment for acne, rosacea and any blistering-type disease.
